I agree with Amy Lynn and Ginger/GenieGirl. The Raleigh/Cary area is a good place to live and very educated. While I've flirted with being en femme in public, I've never gone out fully dressed. But I have followed Ginger's adventures vicariously (we apparently live about 2 miles from each other) and it sounds like she's had no problems being accepted. Unfortunately my family situation precludes me from testing the waters myself.
But as they have said, the weather here is very nice overall (four seasons, with only summer possibly being too extreme) and a booming job market, especially in STEM areas like software and biotech. There are no real tourist attractions here but there are still lots of events of interest.
Please move here and help increase the value of my property.