The biggest underdogs in society?
No, I don't think so. I think that some people have it worse than us.
Some groups with mental illness are probably worse off. Many end up poor and destitute and then are blamed for being in that state. Some racial/ethnic groups still are treated so badly by many as to possibly be listed below us too.
But I don't think we are very far from the bottom.
And what about the TG's with mental illness? The TGs who are homeless? The TG's who belong to racial/ethnic groups that are still frequently despised? Maybe they are the biggest underdogs in society.
So what can be done about it?
a) decry bigotry in all it's forms whenever you see it. Racism, sexism, ablism, homophobia, transphobia... no excuses. If someone makes such a coment, disagree publicly. If you see an injustice, speak and act!
b) consider contributing financially to groups willing to fight for TG (and others) rights and justice
c) irrespective of other politics consider voting, and particularly voting for those who will support, or at the least not oppress, the rights of TG's and all others
d) support trans-positive media representations. Write to companies that publish/produce positive TG images to tell them you approve. Don't just rent or download but make it a point to buy DVD's of positive portrayels of TGs.
e) find some way you can personally advance the cause. Can you help TG's in your workplace? Can you help TGs from your workplace? Do you have any skills or resources that could, even in a tiny way, be put to use to help out TGs in society?