Originally Posted by
Confucius
Your brain is hardwired to interpret cross-dressing as actual contact with a female. So when you cross-dress your brain goes into action releasing neurotransmitters: dopamine is what provides the urges to seek gratification, sexual or otherwise (its also associated with compulsive behavior), then there is serotonin which is associated with sensations of well-being, happiness, reduces stress, and improves sleep, and then there is oxytocin which is associated with social empathy, trust, bonding, and love. The testosterone is associated with your sex drive.
When you orgasm your dopamine levels drop and your prolactin levels to up. Prolactin is associated with the pulling away after sex. So immediately after orgasm you may experience a loss of the pleasure with your cross-dressing. Of course if you wait a few minutes your cross-dressing interests will return.