Billy Crystal played a transsexual on the comedy series "Soap"
His character entered the hospital to have a sex change but changed his mind.
I remember the TV series "Medical Center". In one episode a doctor (played by Robert Reed) announced he was going to have a sex change. I was around ten years old then. I read about the episode in TV guide and was all interested but on the night it was on I stayed away from it because I didn't want my family to know that I was interested in sex changes.