My wife and I were at a wedding this weekend of someone I know.
While the wedding party walked into the church, I noticed the last pair walked in on the opposite side of the bridesmaids and groomsmen, so the woman was standing on the groom's side and the man was standing on the bride's side.
We borrowed a program from the woman in the row in front of us and it listed the wedding party. It showed the bridesmaids, the groomsmen, the maid of honor, AND the Best Woman (the groom's sister) and the Man of Honor (a male friend of the bride's).
I asked the groom about the arrangement after the wedding. He said he had two choices, and his male choice was in Afghanistan, and as he had always been close to his sister, she became the Best Woman. The Man of Honor during the toasts said the bride told him after meeting the groom that he would be here Man of Honor, as they had been friends since 6th grade. Nobody at the wedding made a big deal of it.
So slowly gender barriers are falling. Maybe not as fast as we hope, but day by day.