I've worn nail polish in male-mode many times. Almost always bright red. Men never say anything to me, but I've had several nail-polish discussions with women. One of the most interesting was when I was flying back from Las Vegas after spending a week there fully en femme the entire time. She looked at my hands and said, "Were you performing in Las Vegas?" I answered that I wasn't, and she said "Just having fun then?" Oh yeah! Lots of fun!