My current endo suggested that I eliminate spironolactone and switch to progesterone 4 months ago. His reasoning was that progesterone would enhance feminization and that I could eliminate spiro and it?s side effects. We gradually decreased the spironolactone dosage and switched over to progesterone. I?ve been quite happy with the change. I?ve noticed that my breasts have increased to almost a cup size greater and they are fuller. My skin has become softer and the tone is different - whiter? Losing the spironolactone has eliminated the frequent bathroom breaks. Mentally, I?ve noticed that I?m more at peace with myself. The calm that I felt by going in to estrogen was enhanced. The effects will stop after about a year so we?ll discontinue the progesterone at that point. I?ll consider an orchioectomy at that point.