I read a poll several years ago that suggested that up to 75% of hetro males would elect to be a female for a week or two, provided the change was COMPLETE and they could change back---Quite interesting. We guys are a curious lot.
Back to genetics, If the DNA could be changed, at the very most we could expect "soft tissue" changes. meaning the skin and organs and muscles might change, but the skeleton likely would not. It is mostly a lattice of "minerals" and ceases to grow at maturity. The only bones that MAY grow bigger, as seen in some forms of "giantisim" are the hands, Feet and jaw.---As females they wouldnt GROW anyway.--Indeed we want those to shrink, which they will not do.
Breasts, hips, and fat distribution wouldnt happen, despite complete DNA change, until The Testes athropied and the ovaries developed and started producing hormones.
Another thing to consider, aside from DNA change alone, is the Theory of the "BIOMETRIC FIELD" This has been proposed as an electromagnetic(?) or energy field that causes the individual cells, despite their DNA, to assemble themselves into the correct overall configuration of the organisim.----There MAy be some hope here, as even the skeleton deteriates and is replaced, cell by cell, the biometric Field might influence HOW the structures are replaced.---Eventually, the entire shape of the orgnasim MAY be altered.----It MAy be even more important than DNA in this respect.