If this was 1991 when the movie was made we might have cause to discuss it's impact on the general population. But it's well over twenty years ago now. In any case it's made clear in the movie that like Hannibal Lecter the killer is very much on his own in terms of his madness. The crossdressing is incidental in any case.
You might just as well say that a movie, for example like Magnum Force (Clint Eastwood) gives a negative image of cops.
If you ask me it's movies like Tootsie and Mrs Doubtfire that annoy the hell out of me. I absolutely detest both of them.
