Practically, the physical structure of my body is male and my genetic makeup is XY. So, for medical purposes I'm male. Now, I have a few female things going on too, like estrogen and breasts. I'm an amalgam of both sexes and always will be. Unfortunately, "Amalgam" is not a choice on the form.
For me, dysphoria is not really triggered by practical matters, but by how I am socially perceived.
I'm in my 50s and on HRT. That makes me higher risk for breast cancer, just as it would a GG in the same position.