Teresa, the more you clarify your question, the more it sounds like an acceptance test. But it isn't. As others have said, there are too many unknowns. I would speak, wave, nod, or none of those depending on circumstances, but not on whether the neighbor was crossdressed. If eye contact is made, I would acknowledge in some way. If not, I wouldn't.
I wonder if you are asking because many (most?) of us, at least at one time, ventured out crossdressed but didn't want contact with anyone at all, so would we internationally not speak, wave, or nod to a CDer when we would otherwise, out of an extra measure of respect for privacy?
Are we overthinking this?