I went to a party thrown by a co-worker about 7 years ago. While this pic was a different outing, it is the same outfit and hair and so is very close to what I would have looked like that night. The only difference being that my wife would have done my makeup back then and I would have looked a bit better:
It turned out to be a hugely popular event and there was easily a hundred people there. My wife and I were talking to the hostess, and had been talking to her for about half an hour, when she gets a shocked look on her face and totally interrupts.
"Oh my God! Your a man??!!" she said with this stunned look on her face. My wife and I both just busted out laughing.
"I sure hope so!" I told her "You know since my wife and I have been married for 15 years and have a son and all!"
I swear I'm not kidding, she grabbed my hand and started walking me from room to room, group to group.
"Do you see this beautiful woman? It's a guy!" and off we would trot to the next group.
The thing is, every one at work treated me different after that. Not better, not worse, just different. All in all, I kind of wish I hadn't done it.