At about six months you become sterile. And remember, your results may vary. Like Michele I felt an almost instant placebo effect of 'rightness' and while whatever the physical effects may come I've ALLWAYS been more interested in how HRT would make me feel... would I get in touch with other emotions? I have found that I also couldn't go topless anywhere anymore ( I have a sister who insists that I only come as her brother... Hmmm, I wonder what she would do if I walked out into her back yard and used the jacuzzi in nothing but a speedo? ) I have had some great hair reduction results with my body hair. I've had about a fifty percent in the dark, thick hairs on my arms, legs , and around my navel. Heck, I stopped shaving around the navel and arrms, I know women with more and darker hair than what I have now. So, results may vary... is a true statement. AND I'm only half way through, it takes about three years for all of the changes to be complete. So, I'm a patient girl, But I AM a girl, and THAT'S what get's me through those moments of depression... Carol