HRT shouldn't affect voice or beard. If she had Laser/electrolysis, the beard should have been removed already. If she hasn't had all that done, she could/should continue with that.
The mood swings were part of the reason I stopped HRT 7-8 after SRS. I was on a combo of Estrogen/Progesterone, in a similar to female monthly cycle. My OB/GYN could not see a reason at that time (1985) to continue.
Maybe she needs to have her Endo modify her levels.
